AI钱塘论坛(第34期)
主题:Computational Pathology and Integrative Genomics for Precision Medicine Research
时间:14:00-16:00, 2025年10月17日
地点:行政楼三楼西会议室
主持人:厉力华教授
黄昆博士
于1996年在清华大学获得生物科学和计算机科学双学士学位,随后在伊利诺伊大学香槟分校(UIUC)获得生理学、电子工程学和数学硕士学位, 并于2004年获得UIUC电子与计算机工程博士学位,主要研究方向为计算机视觉和机器学习。其目前担任印第安纳大学医学院PHI基因组数据科学讲席教授,印第安纳大学医学院和费尔班克斯公共卫生学院生物统计学和健康数据科学系主任,同时兼任印第安纳大学西蒙综合癌症中心数据科学副主任及Regenstrief研究所研究员。 他的研究兴趣包括生物图像信息学、计算病理学、转化生物信息学和健康数据科学。他于2018年当选为美国医学和生物工程研究院(AIMBE)会士,2025年当选为美国医疗信息学院(ACMI)会士。共发表研究论文250余篇。
ABSTRACT
Computational pathology is an emerging research area straddling artificial intelligence, computer vision, and biomedical imaging. It has been boosted in recent years by the wide adoption of deep learning technologies. Besides its applications in disease diagnosis and prognosis, computational pathology is a powerful phenotyping tool for quantitatively measuring cellular and tissue morphology in disease tissues such as cancer biopsy samples. The extracted quantitative morphological features can be integrated with omics data to generate new biological hypothesis regarding disease development and new integrative markers predicting clinical outcomes for patients. In this talk, I will give any overview of our work in computational pathology over the past twenty years and recently developed machine learning methods for integrating multi-modal data with applications in multiple cancers and Alzheimer’s disease for predicting biomarkers, clinical outcomes, and drug targets.
